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Monomeric tumor necrosis factor receptors (light blue) get activated after binding TNF (dark blue) and build trimeric complexes. The lighter bottom domains are the death domains. TNF receptors are primarily involved in apoptosis and inflammation.

Monomeric tumor necrosis factor receptors (light blue) get activated after binding TNF (dark blue) and build trimeric complexes. The lighter bottom domains are the death domains. TNF receptors are primarily involved in apoptosis and inflammation.

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